Study of Vitamin C amount in pharmaceutical industries and its matching with manufacturer’s specifications in the prospectus for different companies

الملخص

Vitamin C (Vit C) participates in many biological processes and is an important antioxidant for the human body. It is existent in some species of vegetables and fruits and the most taken nutritional supplement in world, especially during COVID 19. This study aims to estimate amount of Vit C in different pharmaceutical forms and compare it with that aforementioned label on the container for different pharmaceutical companies with different Brand names. These pharmaceutical forms of Vit C were bought from pharmacies in Alhoban-Taiz,Yemen, and were divided to three categories according to the content of Vit C (240, 500, and 1000 mg). After that, they were analyzed using iodometric titration method based on an oxidation-reduction reaction between vitamin C and potassium iodate solution, pure Vit C was used as standard. According to the obtained results, it was found that the calculated contents of Vit C in the pharmaceutical forms were different than those the manufacturer’s specification in the prospectus, the decreases were ranged between 9.12 –23.92% less than those demanded amounts